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What is lung adenocarcinoma? The cancer behind the Pope's surgery, explained

It is the most common form of lung cancer and, caught early, one of the more treatable. Here is what the diagnosis means and why routine check-ups matter.

What is lung adenocarcinoma? The cancer behind the Pope's surgery, explained
Illustration: GlobeHourly

At a glance

  • Adenocarcinoma is the most common type of lung cancer and belongs to the non-small cell group.
  • Among lung cancer types it is generally considered to have the most favourable outlook, especially when found early.
  • The Pope's tumour was found as a small nodule during a routine check, then confirmed by CT, PET and tissue tests.
  • Minimally invasive, video-assisted chest surgery typically needs about 15 to 20 days of recovery.

When the Vatican confirmed that Pope Leo XIV has lung adenocarcinoma, millions of people searched for the same thing: what exactly is it? Here is a plain-language guide.

The most common lung cancer

Lung cancers are broadly split into two groups: small cell and non-small cell. Adenocarcinoma is a non-small cell cancer and is the single most common type. It usually begins in the cells that line the small airways and produce mucus, often in the outer parts of the lungs.

Specialists quoted by the Associated Press said that, among the different lung cancers, adenocarcinoma has the most favourable prognosis — particularly when it is found before it spreads.

How it is usually found

Early lung cancer often causes no symptoms. Many cases are found by chance, the way the Pope's was: a small spot, or nodule, shows up on a scan during a routine check. A nodule is not automatically cancer. Old infections, inflammation and benign growths can all leave marks on a scan.

To tell the difference, doctors typically order a CT scan with contrast, a PET scan to look for active disease, and a biopsy. The Vatican said Leo had all three before his operation.

Treatment for early-stage disease

When the cancer is confined to one area, surgery is the standard first option. Surgeons often remove the affected lobe of the lung — a lobectomy — as happened with the Pope, whose lower right lobe was taken out. Many operations are now done through small incisions using a camera, known as video-assisted thoracoscopic surgery, which shortens hospital stays. A radiation oncologist told the AP that recovery from this type of surgery usually takes about two to three weeks.

Why check-ups matter

The Pope's case is a reminder of the value of routine screening. Many health systems recommend low-dose CT screening for people with a heavy smoking history. If you have a persistent cough, chest pain, breathlessness or unexplained weight loss, speak to a doctor.

This explainer is for general information and is not a substitute for medical advice.

Questions people are asking

Is a lung nodule always cancer?

No. Lung nodules can come from past infections, inflammation or benign growths. Doctors use scans and sometimes a biopsy to decide whether a nodule needs treatment.

How was the Pope's cancer found?

During a routine medical check-up. Doctors spotted a small nodule, ran a contrast CT scan and a PET scan, took tissue samples and recommended surgery while the disease was at an early stage.

What should I do if I'm worried about lung cancer?

Talk to a doctor, particularly if you smoke or used to smoke, or have a persistent cough, breathlessness or unexplained weight loss. This article is general information, not medical advice.

How we verified this story

GlobeHourly wrote this report in its own words after checking the facts against 3 independent sources: official statements, wire agencies and established news outlets. Read our standards.

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